Research Guides: Bioinformatics: Home

Introduction

Bioinformatics is an interdisciplinary field that advances methods for storing, retrieving, and analyzing biological data such as DNA, RNA, protein sequences, structure, function, pathways, and interactions. Bioinformatics is critical to research areas across the life sciences including biomedical research, precision medicine, medicinal chemistry and agriculture. Bioinformatics requires training in biology, computer science, statistics and data science. Several introductory reviews are listed below. You can find more reviews on the Reviews page.

Bioinformatics Curriculum Guidelines: Toward a Definition of Core Competencies (2014)
This article on bioinformatics in the curriculum also discusses career opportunities and several levels of required expertise.
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Welch L, Lewitter F, Schwartz R, Brooksbank C, Radivojac P, Gaeta B, et al. (2014) Bioinformatics Curriculum Guidelines: Toward a Definition of Core Competencies. PLoS Comput Biol 10(3): e1003496. https://doi.org/10.1371/journal.pcbi.1003496
Bioinformatics in the post-sequence era (2003)
This review focuses on the impact of next-generation sequencing on bioinformatics.
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Kanehisa, M., Bork, P. Bioinformatics in the post-sequence era. Nat Genet 33 (Suppl 3), 305–310 (2003). https://doi.org/10.1038/ng1109
A brief history of bioinformatics (2019)
An accessible review of bioinformatics for students in the life sciences.
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Jeff Gauthier, Antony T Vincent, Steve J Charette, Nicolas Derome, A brief history of bioinformatics, Briefings in Bioinformatics, Volume 20, Issue 6, November 2019, Pages 1981–1996, https://doi.org/10.1093/bib/bby063

Bioinformatics in the News

Current news stories in Bioinformatics